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KMID : 0858520110150020091
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Journal of the Korean Society of Magnetic Resonance in Medicine
2011 Volume.15 No. 2 p.91 ~ p.101
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Principles and Technical Aspects of Perfusion Magnetic Resonance Imaging
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Jahng Geon-Ho
Kim Ho-Sung
Kim Sun-Mi
Ryu Chang-Woo
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Abstract
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Perfusion magnetic resonance imaging (pMRI) is a special technique for evaluation of blood flow. Exogenous pMRI methods which are dynamic susceptibility contrast (DSC) and dynamic contrast-enhanced (DCE) use an intravenous bolus injection of paramagnetic contrast agent. In contrast, an endogenous pMRM method which is arterial spin labeling (ASL) use diffusible blood in body. In order to scan pMRI in human, technical optimizations are very important according to disease conditions. For examples, DSC is popularly used in patients with acute stroke due to its short scan time, while DSC or DCE provides the various perfusion indices for patients with tumor. ASL is useful for children, women who are expected to be pregnant, and in patients with kidney diseases which are problematic in nephrogenic systemic fibrosis (NSF). Perfusion MRI does not require any injection of radioisotopes. We expect that demand for perfusion MRI will be higher in evaluating drug efficacy and other treatment effects.
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KEYWORD
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Perfusion MRI, Principle, Technical aspect, DSC, DCE, ASL
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